Diabetes discovery illuminates path to new drugs: To David Altshuler, the recent discovery of a genetic mutation that protects against type 2 diabetes offers hope in fighting more than just diabetes.
It also illustrates how using the tools of genetics to hunt for "broken genes" can aid drug discovery, a process that itself is broken, Altshuler said, with new finds scarce despite billions spent on research.
"Almost everything we put into patients fails," said Altshuler, a Harvard Medical School genetics professor. "There's something wrong with what we're doing."
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